To develop with or without the prion protein

HIGHLIGHTS

• who: Sophie Halliez and Vincent Béringue from the Institut National de la Recherche, Jouy-en-Josas, France have published the research work: To develop with or without the prion protein, in the Journal: (JOURNAL)

SUMMARY

Prion diseases are a group of fatal and transmissible neurodegenerative diseases affecting a broad range of mammals including humans. PrP primary sequence is highly conserved among mammals (Wopfner et_al, 1999) and PrP putative functional domains are structurally conserved between mammals, avians, and fish (Wopfner et_al, 1999; Rivera-Milla et_al, 2006). The production of mice, goat, and cattle . . .

 



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