Toll-like receptor 4 signaling in the trabecular meshwork

HIGHLIGHTS

• who: Philip Mzyk and colleagues from the University of Wisconsin-Madison, Madison, WI, United States, University of Houston-Victoria, Victoria, TX, United States have published the paper: Toll-Like Receptor 4 Signaling in the Trabecular Meshwork, in the Journal: (JOURNAL)
• what: This mechanism of endocytosis of LPS bound TLR4 and its degradation through the ubiquitin pathway is one of the negative regulatory mechanisms in the LPS induced TLR4 pathway, and the purpose of this internalization is to limit the receptor expression and the signaling of the pro-inflammatory MyD88 dependent pathway. To further evaluate the . . .
  

   

  

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