Toll-like receptor 7 (tlr7) is expressed in adipocytes and the pharmacological tlr7 agonist imiquimod and adipocyte-derived cell-free nucleic acids (cfdna) regulate adipocyte function

HIGHLIGHTS

  • who: Miriam Thomalla and collaborators from the Department of Internal Medicine III, Justus-Liebig-University Giessen, Gießen, Germany have published the research work: Toll-like Receptor 7 (TLR7) Is Expressed in Adipocytes and the Pharmacological TLR7 Agonist Imiquimod and Adipocyte-Derived Cell-Free Nucleic Acids (cfDNA) Regulate Adipocyte Function, in the Journal: (JOURNAL)
  • what: The authors aimed to analyze the effects of the pharmacological TLR7 agonist imiquimod, as well as the proposed ligand cfDNA, on adipocyte gene_expression and adipokine concentration in cell-culture supernatants. The authors show that adipocyte differentiation induces the TLR7 mRNA . . .

     

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