HIGHLIGHTS
- who: Sharon L. Ford and collaborators from the Centre for Inflammatory Diseases, Department of Medicine, Monash University, Clayton, VIC, Australia have published the research: Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis, in the Journal: (JOURNAL)
- what: This study investigates dendritic cell TLR9 ligation in murine experimental anti-MPO The authors demonstrate that TLR9 ligation enhances MPO specific dendritic cell activation upregulating CD40 and CD80 expression. The studies demonstrate a modest increase in Th1 responses in the autoimmune phase of TLR9-stimulated MPO-pulsed dendritic-cell-induced disease and . . .
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