HIGHLIGHTS
- who: Li Luo and colleagues from the School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China have published the Article: Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction, in the Journal: Pharmaceuticals 2022, 15, x FOR PEER REVIEW of /2022/
- what: On these grounds, this study explored the effect of TSN on hepatocyte autophagy and the role of autophagy in TSN hepatotoxicity. The study demonstrated that TSN induced obvious hepatotoxicity through TFEB-lysosome-mediated autophagic flux blockade.
- how: The data showed that TSN did not affect the . . .
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