HIGHLIGHTS
- who: Yufeng Zhang from the Institutes of Health (NIH), United States Shanghai Jiao Tong University, China have published the research: TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma, in the Journal: (JOURNAL)
- what: The authors investigated whether TOP2A affects the radioresistance of MB cells through the Wnt/b-catenin signaling pathway. In the present study, si-TOP2A-transfected MB cells were exposed to 8 Gy IR, and the results showed that si-TOP2A transfection in combination with IR exposure obviously reduced the proliferation, migration and invasion ability of Daoy cells compared with those . . .
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