Top2b is required to maintain the adrenergic neural phenotype and for atra-induced differentiation of sh-sy5y neuroblastoma cells

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  • who: Mushtaq M. Khazeem from the The Faculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne , HH, UK have published the Article: TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells, in the Journal: (JOURNAL)
  • how: To test the requirement for TOP2 activity in ATRAinduced gene_expression SH-SY5Y cells were treated with ATRA as before but also with either the TOP2 catalytic sion data was calculated relative to the control housekeeping gene PP1A. Differential Expression Analysis To fully explore both differences in gene_expression . . .

     

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