Topical application of daphnetin hydrogel for traumatic brain injury

HIGHLIGHTS

  • What: The article describes the establishment of weight drop injury (WDI) using a modified version of Feeney`s weight-drop method, as previously reported (Feeney et_al, 1981; Marmarou et_al, 1994). As seen in Figures 4A,B, the BBB permeability of the injured lateral hemisphere was significantly reduced in both ip Dap and TM/Dap hydrogel treatment groups compared with the TBI and TM groups, and the TM/Dap hydrogel treatment group significantly suppressed the Evans blue leaking, limiting the area of leakage to the site of the primary focus.
  • Who: Yuanhao Ma from the The . . .

     

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