Topical application of tetrandrine nanoemulsion promotes the expansion of cd4+foxp3+ regulatory t cells and alleviates imiquimod-induced psoriasis in mice

HIGHLIGHTS

• who: Shaokui Chen and colleagues from the Pohang University of Science and ShanghaiTech University, China have published the paper: Topical Application of Tetrandrine Nanoemulsion Promotes the Expansion of CD4+Foxp3+ Regulatory T Cells and Alleviates Imiquimod-Induced Psoriasis in Mice, in the Journal: (JOURNAL)
• how: The result showed that topical administration of TET NE potently inhibited the mouse psoriasis-like disease induced by imiquimod (IMQ) which is associated with the expansion of Tregs and inhibition of inflammatory responses. Data were analyzed using FlowJo software (Tree Star Inc []. The immunofluorescent results indicated that the infiltration of . . .
  

   

  

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