Topical capsaicin in poly(lactic-co-glycolic)acid (plga) nanoparticles decreases acute itch and heat pain

HIGHLIGHTS

  • who: Nathalie M. Malewicz et al. from the Department of Anesthesiology, Yale University School of Medicine, Cedar St, New Haven, CT, USA have published the article: Topical Capsaicin in Poly(lactic-co-glycolic)acid (PLGA) Nanoparticles Decreases Acute Itch and Heat Pain, in the Journal: (JOURNAL)
  • what: In this study, capsaicin-loaded PLGA NPs were developed for topical application in humans and their in_vitro physicochemical attributes were characterized. For the analysis of skin penetration of the NPs, either capsaicin, blank or capsaicin NPs each encapsulated with a dye (DiL) were applied to the cheek of . . .

     

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