Topoisomerase 2β and dna topology during b cell development

HIGHLIGHTS

  • who: Olivier Papapietro from the University of Texas Health Science Center at San Antonio, United States have published the research: Topoisomerase 2u03b2 and DNA topology during B cell development, in the Journal: (JOURNAL)

SUMMARY

    Although TOP2B drives gene_expression, frequently associates with cell type-specific TFs and occupies open chromatin regions, it does not act as a classical TF. There is now concordant evidence implicating TOP2B in regulation of transcriptional programs far beyond the nervous system acting at several critical points that control gene_expression. (A) TOP2B activities include DNA decatenation, e_g in separation of . . .

     

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