Topoisomerase iiβ targets dna crossovers formed between distant homologous sites to induce chromatin opening

HIGHLIGHTS

• who: Mary Miyaji from the Graduate SchoolOkayama University, Niigata, Japan have published the research: Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening, in the Journal: Scientific Reports Scientific Reports
• what: The authors adopt this model as a presupposition to interpret the data obtained. The authors propose a model that implies the presence of two distinct topo II-involved processes: formation and disruption of higher order chromosomal structures (Fig 6).
• how: All animal experiments were conducted in accordance with the Guidelines specified by the Regulation for Animal Experiments . . .
  

   

  

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