Total syntheses of the proposed structure of iriomoteolide-1a, -1b and synthesis of three derivatives for structural studies

HIGHLIGHTS

• who: Arun K. Ghosh and Hao Yuan from the Department of Chemistry, Department of Medicinal Chemistry, Purdue University, West Lafayette, IN, USA have published the research work: Total Syntheses of the Proposed Structure of Iriomoteolide-1a, -1b and Synthesis of Three Derivatives for Structural Studies, in the Journal: (JOURNAL)
• what: The authors report far, neither the biological mechanism of action nor the correct structures of iriomotelides the revised syntheses of the proposed structures of iriomoteolide-1a and -1b.
• how: A SnCl4 -mediated ene reaction of aldehyde 7 and olefin 8 was carried out . . .
  

   

  

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