Toward scalable biocatalytic conversion of 5-hydroxymethylfurfural by galactose oxidase using coordinated reaction and enzyme engineering

HIGHLIGHTS

  • who: William R. Birmingham from the SchoolThe University have published the paper: Toward scalable biocatalytic conversion of 5-hydroxymethylfurfural by galactose oxidase using coordinated reaction and enzyme engineering, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • how: Source data are provided with this paper.

SUMMARY

    Building on the previous work in understanding the effect of reaction conditions on GOase for alcohol oxidation (critically, the inclusion of horseradish peroxidase (HRP) to activate GOase and catalase to remove destructive H2O2)42, the authors have engineered GOase for improved kinetic properties for both alcohol oxidation . . .

     

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