Towards a better understanding of cohesin mutations in aml

HIGHLIGHTS

  • who: Sergi Cuartero and Matthias Merkenschlager from the Faculty of Medicine, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Imperial College London, Haematology, Imperial College London, London, United Kingdom University Hospital Münster, Germany have published the Article: Towards a Better Understanding of Cohesin Mutations in AML, in the Journal: (JOURNAL)

SUMMARY

    Hematopoietic homeostasis requires tight regulation to ensure production of sufficient numbers of blood cells at all stages of differentiation. Skewing of this balance in favor of excessive differentiation results in stem_cell depletion, exhaustion and eventually, inability to replenish mature . . .

     

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