Towards a new 3rs era in the construction of 3d cell culture models simulating tumor microenvironment

HIGHLIGHTS

  • who: Long Zhang et al. from the Swiss R Competence Centre, Switzerland Southern Illinois University Carbondale have published the research: Towards a New 3Rs Era in the construction of 3D cell culture models simulating tumor microenvironment, in the Journal: (JOURNAL)
  • what: For the study of tumor initiation, smaller, well-oxygenated spheres (optimal diameter of about 200mm) can be used. The activity, proliferation of investigated cells were increased Peptide hydrogel Max8b was used as hydrogel to form nanofibrils through hydrophobic collapse and hydrogen_bonding Custom hydrogels for porosity, permeability and mechanical stability Soluble gelatin based cell carrier . . .

     

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