Towards immunotherapy-induced normalization of the tumor microenvironment

HIGHLIGHTS

  • who: Vinicio Melo and colleagues from the Department of Hematology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, Materia Therapeutics, Las Vegas, NV, United States have published the article: Towards Immunotherapy-Induced Normalization of the Tumor Microenvironment, in the Journal: (JOURNAL)
  • what: This study provides an additional hypothesis for a feedback loop between T_cells and vascular normalization.
  • future: Research is necessary to determine whether and how these immunotherapies are combinable for enhanced vascular normalization SDF1u03b1/CXCR4 pathway (Chen et_al 2015).

SUMMARY

    Accordingly, hypoxia is associated with poor survival . . .

     

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