Towards sequence-based prediction of mutation-induced stability changes in unseen non-homologous proteins

HIGHLIGHTS

  • who: Folkman et_al BMC Genomics and collaborators from the (UNIVERSITY) have published the research work: Towards sequence-based prediction of mutation-induced stability changes in unseen non-homologous proteins, in the Journal: (JOURNAL)
  • what: The authors focused the attention on the sequence-based methods. The authors provided experimental evidence of the limitations of the evaluation commonly used for assessing the prediction performance. The authors proposed a method referred to as EASE-AA: Evolutionary And Structural Encodings with Amino Acid parameters.
  • how: To improve the prediction performance of the previously proposed method the authors . . .

     

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