HIGHLIGHTS
- who: Vincent Courdavault from the (UNIVERSITY) have published the Article: Towards the Microbial Production of Plant-Derived Anticancer Drugs, in the Journal: (JOURNAL)
- future: Push towards a monocytic lineage was as- this exciting work adds a new perspective sociated with an increased bioenergetic on the key contribution of myeloid-intrinsic profile and higher cholesterol activity in PD1 signaling to immune evasion in cancer.
SUMMARY
To study myeloid cell-expressed PD1 in myelopoiesis and tumor growth, the authors generated myeloid cell-specific PD1deficient mice. Similar to global PD1deficient mice, myeloid cell PD1 . . .
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