Toxoplasma gondii gra7-targeted asc and pld1 promote antibacterial host defense via pkcα

HIGHLIGHTS

  • who: Hyun-Jung Koh et al. from the Department of Molecular and Life Science, College of Science and Technology, Hanyang University have published the Article: Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCu03b1, in the Journal: (JOURNAL) of January/26,/2017
  • what: The authors show that protein kinase C (PKC)u03b1-mediated phosphorylation of T. GRA7-I (Ser52) regulates the interaction of with PYD domain of apoptosis-associated speck-like protein containing a carboxy-terminal CARD which is capable of oligomerization and inflammasome activation can lead to antimicrobial against MTB . . .

     

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