Toxoplasma gondii microneme protein mic3 induces macrophage tnf-α production and ly6c expression via tlr11/myd88 pathway

HIGHLIGHTS

  • who: Jingfan Qiu and collaborators from the University, Nanjing, Jiangsu, China have published the research: Toxoplasma gondii microneme protein MIC3 induces macrophage TNF-u03b1 production and Ly6C expression via TLR11/MyD88 pathway, in the Journal: (JOURNAL)
  • what: The authors found that a peptide of T. induced NF-u03baB phosphorylation iNOS transcription and Ly6C in mouse macrophage RAW264.7 cells. inhibition small interfering RNA against and CRISPR/Cas9mediated knock-out of reduced MIC3-induced NF-u03baB phosphorylation iNOS transcription and Ly6C Additionally the authors determined the location of peptide in mouse macrophages using immunofluorescence. could both . . .

     

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