Tppu inhibits inflammation-induced excessive autophagy to restore the osteogenic differentiation potential of stem cells and improves alveolar ridge preservation

HIGHLIGHTS

  • who: Haixia Dang from the Medical University have published the Article: TPPU inhibits inflammation-induced excessive autophagy to restore the osteogenic differentiation potential of stem cells and improves alveolar ridge preservation, in the Journal: Scientific Reports Scientific Reports
  • what: Our results confirm that TPPU restored impaired osteogenic differentiation potential of hDPSCs caused by inflammation-induced excessive autophagy.
  • how: The results showed that TPPU had no significant effect on cell viability of hDPSCs with or without LPS. The results showed that rapamycin exacerbated poor osteogenesis due to autophagy in an inflammatory environment while TPPU . . .

     

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