Tracheostomy in children is associated with neutrophilic airway inflammation

HIGHLIGHTS

  • who: Jason Powell u200d u200d and collaborators from the Newcastle University, Newcastle have published the article: Tracheostomy in children is associated with neutrophilic airway inflammation, in the Journal: (JOURNAL)
  • what: The authors aimed to characterise airway host defence in tracheostomised children using serial molecular analyses. The study shows for the first time that, in children, long-u00adterm tracheostomy is associated with neutrophilic inflammation, active proteolysis, sustained superoxide production and airway dysbiosis. u21d2 These data suggest an association between airway host defence dysregulation, microbiological changes and airway infections. The aims of this study were therefore to . . .

     

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