Trail receptors promote constitutive and inducible il-8 secretion in non-small cell lung carcinoma

HIGHLIGHTS

  • who: Francesca Favaro from the (UNIVERSITY) have published the research: TRAIL receptors promote constitutive and inducible IL-8 secretion in non-small cell lung carcinoma, in the Journal: (JOURNAL) of 13/05/2022
  • what: The authors show here that this inhibitor also had an effect under basal conditions (Fig 2D and Fig S2C). The authors aimed to identify which of these pathways were maintained by tonic activation of TRAIL receptors, with or without TRAIL. The authors show that several lung cancer cells with diverse mutational Ras status and WT EGFR secrete the chemokine IL-8 . . .

     

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