HIGHLIGHTS
- What: The aim of this narrative review is to provide a summary of the literature on TXA to give Frontiers in Medicine frontiersin.org 10.3389/fmed.2024.1416998 Tranexamic acid healthcare professionals all the information they need about its use. While TXA has been studied in numerous small retrospective and prospective studies, the authors focused on the largest and most recent trials with the greatest therapeutic impact. When seizures were first observed, highdose boluses up to 100 mg/kg were the norm in cardiac surgery, as evidenced by the initial protocol of the study led by . . .

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