Trans-endothelial migration of memory t cells is impaired in alemtuzumab-treated multiple sclerosis patients

HIGHLIGHTS

  • who: Kristy Nguyen and colleagues from the The University of Sydney, Sydney, NSW, Australia have published the paper: Trans-Endothelial Migration of Memory T Cells Is Impaired in Alemtuzumab-Treated Multiple Sclerosis Patients, in the Journal: (JOURNAL) of 24/Oct/2022
  • what: The authors investigate the migratory capacity of T_cell subsets, including nau00efve T (Tnau00efve ) cells, effector memory (TEM ) cells, central memory (TCM ), and effector memory cells re-expressing CD45RA (TEMRA ) in alemtuzumab-treated patients.
  • how: In this study a transmigration assay was used to examine lymphocyte migration across the BBB as shown . . .

     

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