HIGHLIGHTS
- who: Youngsil Choi from the (UNIVERSITY) have published the Article: Trans-regulation of Syndecan Functions by Hetero-oligomerization*, in the Journal: (JOURNAL) of December/25,/2014
- how: 22-24) the authors investigated whether hetero-oligomerization of syndecans might affect syndecan-2-mediated signal_transduction involved in the regulation of tumorigenic activity. Similar to the observed effects on syndecan-4 signaling the results showed that induction of hetero-oligomerization through co-overexpression of syndecan-2 and -4 significantly reduced the membrane localization of Tiam1 (T-cell lymphoma invasion and metastasis 1) (Fig 7C) and activation of Rac . . .
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