Transcription dependent loss of an ectopically expressed variant surface glycoprotein during antigenic variation in trypanosoma brucei

HIGHLIGHTS

• who: Emilia Jane Mclaughlin et al. from the LHajduk, University of Georgia of Parasites and Insect Vectors, Paris, France have published the research work: Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei, in the Journal: (JOURNAL) of 20/04/2022
• what: Unexpectedly the authors report that in the double VSG-expressing cells the DNA sequence of the ectopic copy lost following DSB in the active BES despite it being spatially separated in the genome. The authors propose that there are stringent mechanisms within the cell to reinforce . . .
  

   

  

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