Transcription factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content

HIGHLIGHTS

• who: Fabio Papes from the Institut University of Campinas, Campinas, Sao Paulo, Brazil have published the research: Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors focused the analyses on six annotated cellular subpopulations in CtOs and GbOs (Fig 3a and Supplementary Fig 3a-c), which compose distinct glutamatergic and GABAergic lineages, each with neural progenitors that progress through an intermediate progenitor stage towards the generation of neurons, as judged by differentiation trajectory analysis (Fig 3b). The . . .
  

   

  

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