Transcription factor sp2 potentiates binding of the tale homeoproteins pbx1:prep1 and the histone-fold domain protein nf-y to composite genomic sites

HIGHLIGHTS

• who: Sara Völkel from the (UNIVERSITY) have published the paper: Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites, in the Journal: (JOURNAL) of August/13,/2018
• what: The authors report DNA binding-independent genomic loading of Sp2 to a composite motif (DECAext motif), which is bound by the dimeric TALE transcription factor Pbx1: Prep1 and Nf-y. The authors show that Sp2 potentiates genomic binding of Pbx1:Prep1 and Nf-y to a composite motif, where the Pbx1:Prep1 . . .
  

   

  

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