Transcription factors runx1 and runx3 suppress keratin expression in undifferentiated keratinocytes

HIGHLIGHTS

  • who: Eisaku Ogawa et al. from the Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan have published the research: Transcription Factors Runx1 and Runx3 Suppress Keratin Expression in Undifferentiated Keratinocytes, in the Journal: (JOURNAL) of 30/05/2022
  • what: The authors investigated the possible functions of and in keratinocyte differentiation. The authors used primary cultures of mouse keratinocytes and demonstrated that both Runx1 and Runx3 proteins were expressed and localized in the nuclei of undifferentiated keratinocytes but translocated to the cytoplasm in differentiated keratinocytes.
  • how: The results showed that Runx1 and . . .

     

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