Transcription tuned by s-nitrosylation underlies a mechanism for staphylococcus aureus to circumvent vancomycin killing

HIGHLIGHTS

  • who: Xueqin Shu from the (UNIVERSITY) have published the research: Transcription tuned by S-nitrosylation underlies a mechanism for Staphylococcus aureus to circumvent vancomycin killing, in the Journal: (JOURNAL) of 12/01/2022
  • what: This study demonstrated endogenous S-nitrosylation as a key mechanism for regulation of vancomycin resistance in S. aureus and as an important area of future bacterial research. This study provides a key insight that bacteria may use host-produced NO to resist antibiotic killing during infection.
  • how: These results indicated that low-concentration NO and the induction of MgrA . . .

     

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