Transcriptional landscape of oncogene-induced senescence: a machine learning-based meta-analytic approach

HIGHLIGHTS

• who: Yeaeun Han from the Department of Biochemistry, Konkuk University School of Medicine, Seoul, South Korea Department of Genetics, University of Cambridge, EH, UK have published the research: Transcriptional landscape of oncogene-induced senescence: a machine learning-based meta-analytic approach, in the Journal: (JOURNAL)
• what: The study provides robust transcriptomic evidence to the unexpected proposition that OIS phenotype may be dominant in tumor cells. The authors show that this OIS-specific phenotype is clearly expressed across various stages of cancer and in the view that u2018senescence escape` of cancer cells leads to tumorigenesis, the . . .
  

   

  

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