Transcriptional regulation of gdf15 by egr1 promotes head and neck cancer progression through a positive feedback loop

HIGHLIGHTS

• who: Yanli Jin et al. from the Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Korea have published the paper: Transcriptional Regulation of GDF15 by EGR1 Promotes Head and Neck Cancer Progression through a Positive Feedback Loop, in the Journal: (JOURNAL)
• what: The study showed that the signaling axis may be a good target in HNC patients. In Figure 5G,H, the authors show that EGR1 overexpressed, with increased phosphorylation of ERK and AKT after treatment with rhGDF15. The authors focused on EGR1 a transcription factor upstream regulator of GDF15 in HNC . . .
  

   

  

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