Transcriptome alterations in peripheral blood b cells of patients with multiple sclerosis receiving immune reconstitution therapy

HIGHLIGHTS

• who: Michael Hecker from the The study population comprised , patients with MS and , healthy controls aged over , yearsIn this cohort, we have already investigated the effects of MS-associated genetic variants on the processing of RNAs, as described in detail in our previous publications [42, ]. Patient care and treatment followed routine clinical practice at the Rostock University Medical Center. In brief, the diagnosis of MS was confirmed based on the revised McDonald criteria [3]. The patients were monitored for the occurrence of relapses, and their degree of neurological disability was rated with the Expanded Disability Status Scale . . .
  

   

  

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