Transcriptome and pan-cancer system analysis identify pm2.5-induced stanniocalcin 2 as a potential prognostic and immunological biomarker for cancers

HIGHLIGHTS

  • who: PM and collaborators from the University of Macau, China have published the research work: Transcriptome and pan-cancer system analysis identify PM2.5-induced stanniocalcin 2 as a potential prognostic and immunological biomarker for cancers, in the Journal: (JOURNAL)
  • how: The authors identified STC2 as a key gene regulated by PM2.5 based on transcriptome analysis whose expression correlated to prognosis immune microenvironment tumor heterogeneity and stemness immune checkpoint genes epigenetic modifications in multiple cancer types. The results showed that the protein and transcript levels of STC2 were up-regulated by PM2.5 exposure . . .

     

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