Transcriptome-based dissection of intracranial aneurysms unveils an “immuno-thermal” microenvironment and defines a pathological feature-derived gene signature for risk estimation

HIGHLIGHTS

• who: Taoyuan Lu from the Shanghai Jiao Tong University, China have published the research: Transcriptome-Based Dissection of Intracranial Aneurysms Unveils an u201cImmuno-Thermalu201d Microenvironment and Defines a Pathological Feature-Derived Gene Signature for Risk Estimation, in the Journal: (JOURNAL)
• what: To quantitatively assess the diagnostic and predictive value of the model, the authors conducted an ROC curve analysis of PFDGS and 15 initial candidate marker genes. The authors systematically identified a blood-based gene risk signature derived from DEGs associated with three aspects of IA pathological features, encompassing immune activation, contractile SMC loss, as . . .
  

   

  

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