HIGHLIGHTS
SUMMARY
The authors found that Tregs were higher in the PCM1-D group compared to PCM1-U, which makes sense since M1 macrophage and T_cell fractions were also significantly lower in the PCM1-D group. While IFN-γ- or TNF-α-producing γδ T_cells can inhibit acute and chronic HBV infection, human CD4-CD8-γδ T_cells and mouse IL-17-producing Vγ4 T_cell subsets contribute to the progression of chronic HBV infection. As the authors found a higher level of gamma delta T_cells in the PCM1-U group that had more inflammation and cellular proliferation and thus a . . .
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