Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis

HIGHLIGHTS

  • who: Colon and colleagues from the Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands have published the Article: Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis, in the Journal: (JOURNAL) of 14/04/2022
  • what: The authors aimed to dissect the transcriptional Leiden University Medical and immunologic alterations that accompany malignant Center Leiden The authors provide evidence for a shift in macrophage populations during the stepwise progression from normal tissue to CRC, accompanied by the upregulation of the CD47/SIRPu03b1 axis. In collaboration with Fight Colorectal Cancer (https . . .

     

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