Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models

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• who: Liliana Capinha from the (UNIVERSITY) have published the article: Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models, in the Journal: (JOURNAL)
• what: In this study six human derived cell models were evaluated as in vitro models representing potential target tissues of TCE-conjugates: RPTEC/TERT1 (kidney) HepaRG (liver) HUVEC/TERT2 (vascular endothelial) LUHMES (neuronal dopaminergic) human induced pluripotent stem cells (hiPSC) derived peripheral neurons (UKN5) and hiPSCderived differentiated brain cortical cultures containing all subtypes of neurons and astrocytes (BCC42). The . . .
  

   

  

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