Transcriptomic diversity in human medullary thymic epithelial cells

HIGHLIGHTS

• who: Jason A. Carter from the Spring Harbor Laboratory University, Stony Brook, NY, have published the Article: Transcriptomic diversity in human medullary thymic epithelial cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: They identified RBFOX splicing factors as influential on TEC development, and the analysis shows the same differential expression of RBFOX1 in human as in mice, a finding worth future investigation. The study has demonstrated several mechanisms that underlie the generation of transcriptomic diversity in human mTECs.
• how: The authors identified a total of 7063 TRA-genes and 35497 TRA-transcripts . . .
  

   

  

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