Transcriptomic profiling of calcified aortic valves in clonal hematopoiesis of indeterminate potential carriers

HIGHLIGHTS

  • who: Francesco Vieceli Dalla Sega from the Department University of have published the research work: Transcriptomic profiling of calcified aortic valves in clonal hematopoiesis of indeterminate potential carriers, in the Journal: Scientific Reports Scientific Reports
  • what: This study aimed to gain insights into the pathological process of CAVD in CHIP carriers. The authors compared the aortic valve transcriptome of CAVD patients in the presence or absence of CHIP mutations.
  • future: The discovery of the possible involvement of inflammation and humoral immunity observed in a relevant fraction of CHIP subjects with CAVD may open . . .

     

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