Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

HIGHLIGHTS

  • who: Alice E. Adriaenssens from the UK University of Copenhagen, Copenhagen, Denmark have published the Article: Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets, in the Journal: (JOURNAL)
  • what: The aim of this study was to identify regulatory proteins and receptors underlying secretion though the use of transcriptomic comparison of purified murine alpha beta and delta cells.
  • how: Ghrelin inhibited insulin and glucagon secretion in an SST-dependent manner To establish a physiological role for delta cell specific activation . . .

     

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