Transfer of mesenchymal stem cell mitochondria to cd4

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  • who: Waseem Akhter from the Institute for Regenerative Medicine and Biotherapy (IRMB), Universitu00e9 de Montpellier, Montpellier, France have published the Article: Transfer of mesenchymal stem cell mitochondria to CD4, in the Journal: (JOURNAL)
  • what: This study shows that transfer of MSC mitochondria to activated C u00ad D4+ T cells results in the suppression of Th1 responses in part by downregulating T-bet expression. The authors report that bone marrow derived allogeneic MSCs transfer mitochondria to C u00ad D4+ Th1-like cells and suppress their activation in response to TCR and costimulation signaling. The authors show . . .

     

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