Transgenic mouse models expressing human and macaque prion protein exhibit similar prion susceptibility on a strain-dependent manner

HIGHLIGHTS

  • who: Juan Carlos Espinosa from the Centro have published the Article: Transgenic mouse models expressing human and macaque prion protein exhibit similar prion susceptibility on a strain-dependent manner, in the Journal: Scientific Reports Scientific Reports of 27/09/2019
  • what: In this work, the transmission features of a collection of TSE isolates, representing a panel of diverse prion strains, is compared in two transgenic mouse experimental models expressing either macaque-PrPC or human-PrPC.
  • how: This study was carried out in accordance with the Directive 2010/63/EU.

SUMMARY

     

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