HIGHLIGHTS
- who: Pierre Sarradin and collaborators from the Génétique Animale Biologie, France have published the research work: Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie, in the Journal: (JOURNAL) of February/11,/2015
- what: The authors report that rabbits engineered to express transgenetically the V136R154Q171 ovine PRNP allele develop a TSE syndrome upon experimental inoculation with scrapie. The authors show that transgenic rabbits expressing a scrapie-susceptible ovine PRNP allele develop, at full attack rate, classical hallmarks of TSEs upon inoculation with scrapie prions, including fatal neurological diseases, clinical signs, PrPres deposition and . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.