HIGHLIGHTS
- who: Aparna Shinde from the IACUC approval from Purdue University was received for conducting all in vivo assays, parental and HME2-BM cells were engrafted into the duct of the second mammary fat pad of, week old female, NSG mice (, u00d7 u00ad, , u00b5l, mouse). When tumors reached , u00admm3, mice an oral gavage of neratinib (, mg/ kg/q.o.d). Neratinib was first solubilized in DMSO, and, .25% Tween-80, .5% carboxymethyl cellulose solution was used for oral gavage at a final DMSO concentration of, %. In separate experiments, female, week old NSG mice were engrafted with HME2-BM . . .
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