HIGHLIGHTS
- who: Tsepo L. Tsekoa from the Aarhus University, Denmark have published the paper: Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9, in the Journal: (JOURNAL)
- what: This study demonstrated the transient production of CAP256-VRC26.25, produced in the glycoengineered N. benthamiana (1XTFT) with human tyrosyl protein sulfotransferase 1 (hTPST1), as was demonstrated with the CAP256-VRC26.08 and CAP256-VRC26.09 bNAbs (Singh et_al, 2020). Through the simultaneous targeted transient disruption of NbCysP6, NbVPE-1a and NbVPE-1b, using clustered regularly interspaced short palindromic repeats/CRISPR associated protein . . .
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