Transient receptor potential channels, natriuretic peptides, and angiotensin receptor-neprilysin inhibitors in patients with heart failure

HIGHLIGHTS

  • who: Lihong Wang from the The University of Manchester, United Kingdom have published the article: Transient Receptor Potential Channels, Natriuretic Peptides, and Angiotensin Receptor-Neprilysin Inhibitors in Patients With Heart Failure, in the Journal: (JOURNAL)
  • what: The research shows that inhibition of TRPC6 activity mediates the antihypertrophic effects of ANP/BNP and suggests that inhibition of TRPC6 may prevent pathological effects, providing insights into potential effective treatment strategies for myocardial hypertrophy and remodeling . The research shows that functional NPR-A/B/C is expressed in mouse DRG neurons, and CNP and ANP, but not BNP . . .

     

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