Transient receptor potential vanilloid type 4 (trpv4) promotes tumorigenesis via nfat4 activation in nasopharyngeal carcinoma

HIGHLIGHTS

• who: TRPV et al. from the Jiangmen Central Hospital, China University of Alabama at Birmingham have published the paper: Transient receptor potential vanilloid type 4 (TRPV4) promotes tumorigenesis via NFAT4 activation in nasopharyngeal carcinoma, in the Journal: (JOURNAL)
• what: The study demonstrates for the first time that TRPV4 promotes NPC cell growth via the Ca 2+ /calcineurin/NFAT4 axis, and highlights the therapeutic potential of targeting the TRPV4/ Ca 2+ /calcineurin/NFAT4 signaling pathway.

SUMMARY

TRPV4 links calcium signaling to DDX3X activity, which is essential for cancer-associated EBV infections (Donate . . .

 



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